BDBM50182571 2-pyrrolidin-1-yl-1-(4-thiophen-2-yl-phenyl)pentan-1-one::CHEMBL369997

SMILES CCCC(N1CCCC1)C(=O)c1ccc(cc1)-c1cccs1

InChI Key InChIKey=HEFDYDISPNHKAM-UHFFFAOYSA-N

Data  3 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182571   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50182571(2-pyrrolidin-1-yl-1-(4-thiophen-2-yl-phenyl)pentan...)
Affinity DataKi:  460nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50182571(2-pyrrolidin-1-yl-1-(4-thiophen-2-yl-phenyl)pentan...)
Affinity DataIC50:  539nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed